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Updated: Aug 18, 2026

Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

Published on: January 3, 2018

Synthesis and cognition activating properties of some mono- and bicyclic lactam derivatives

C Altomare1, A Carotti, G Casini

  • 1Dipartimento Farmaco-Chimico, University of Bari, Italy.

Journal of Medicinal Chemistry
|November 1, 1988
PubMed

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Structures of Carboxylic Acid Derivatives

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α-Substituted ketones or aldehydes can be synthesized from enamines by the Stork enamine reaction, named after its pioneer Gilbert Stork. Enamines are useful synthetic intermediates where the lone pair on nitrogen is in conjugation with the C=C bond. They resemble enolate ions, as the resonance forms of both species have a nucleophilic α carbon.
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