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Unilateral Condylar Hyperplasia: A Comparison With Two Open-Source Softwares.
Valentino Vellone1, Ambra Maria Costantini2, Valerio Ramieri1
1Maxillo-Facial Surgery Department.
The Journal of Craniofacial Surgery
|December 17, 2019
Summary
This study compared manual and semi-manual segmentation methods for calculating condyle volume in unilateral condylar hyperplasia (UCH). Both Horos and ITK-SNAP software showed similar trends, with stronger correlations for healthy condyles.
Area of Science:
- Dentistry
- Medical Imaging
- Orthodontics
Background:
- Unilateral condylar hyperplasia (UCH) is a condyle disorder characterized by osteoblastic hyperactivity.
- UCH leads to significant facial asymmetry, malocclusion, and functional deficits.
- Accurate volumetric assessment is crucial for understanding UCH progression and treatment planning.
Purpose of the Study:
- To compare the accuracy of manual segmentation versus semi-manual segmentation using open-source software (Horos and ITK-SNAP) for condyle volume calculation in UCH patients.
- To analyze volumetric differences between affected and unaffected condyles, and explore variations based on gender, age, and UCH classification.
- To evaluate the reliability and consistency of two different open-source software tools in UCH condyle volumetry.
Main Methods:
- Retrospective analysis of 80 UCH condyles from 40 patients.
- Comparison of "gold standard" manual segmentation with semi-manual segmentation using Horos and ITK-SNAP software.
- Volumetric measurements were analyzed for differences related to affected vs. unaffected sides, gender, age, and UCH classification (transversal, vertical, combined).
Main Results:
- Both Horos and ITK-SNAP demonstrated comparable trends in condyle volume measurements, despite minor differences.
- The correlation between segmentation methods was stronger for healthy condyles than for affected condyles.
- UCH affected the right side more frequently (60%) than the left side (40%).
- Transversal type UCH was most common (67.5%), followed by vertical (25%) and combined types (7.5%).
Conclusions:
- Semi-manual segmentation using open-source software like Horos and ITK-SNAP offers a viable alternative for condyle volume assessment in UCH.
- While minor discrepancies exist between software, the overall trends in volumetric data are consistent.
- Further research may refine semi-manual techniques for improved accuracy and clinical application in managing UCH.

