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Idiopathic Intracranial Hypertension and Anemia: A Matched Case-Control Study
Weijie Violet Lin1, Shauna Berry, Mohammad Obadah Nakawah
1Departments of Medicine, Surgery, and Pediatrics (WVL), Santa Clara Valley Medical Center, Stanford University Hospitals, San Jose, California; Blanton Eye Institute (SB, AS, AGL), Houston Methodist Hospital, Houston, Texas; Houston Methodist Neurological Institute (MON), Houston Methodist Hospital, Houston, Texas; Departments of Ophthalmology (AGL), Neurology, and Neurosurgery, Weill Cornell Medical College, New York, New York; Department of Ophthalmology (AGL), Utah Medical Branch, Galveston, Texas; Department of Ophthalmology (AGL), Utah Maryland Anderson Cancer Center, Houston, Texas; Department of Ophthalmology (AGL), Baylor College of Medicine, Houston, Texas; Department of Ophthalmology (AGL), Center for Space Medicine, Houston, Texas; Department of Ophthalmology (AGL), Texas A&M College of Medicine, College Station, Texas; and Department of Ophthalmology (AGL), University of Iowa Hospitals and Clinics, Iowa City, Iowa.
This study found no significant link between idiopathic intracranial hypertension (IIH) and anemia. Complete blood count values were similar between IIH patients and controls, suggesting anemia is not directly associated with IIH.
Area of Science:
- Neurology
- Hematology
Background:
- Previous reports suggested a link between idiopathic intracranial hypertension (IIH) and anemia.
- Retrospective studies lacked matched controls for standardized complete blood count (CBC) comparison.
Purpose of the Study:
- To compare CBC values between patients with IIH and a matched control group.
- To investigate the potential association between IIH and anemia using standardized laboratory data.
Main Methods:
- A retrospective, matched case-control study was conducted.
- 50 patients with IIH were compared with 50 control patients.
- Standardized CBC parameters were analyzed.
Main Results:
- No significant differences in CBC parameters were observed between IIH and control groups.
- Red blood cell count, hemoglobin, and hematocrit values trended lower in female IIH and control patients, and male IIH patients, but not male controls.
Conclusions:
- This study found no significant association between IIH and anemia based on standardized CBC values.
- The higher prevalence of anemia in the IIH population may be attributed to demographic factors, particularly females of child-bearing age.
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