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Updated: Jan 1, 2026
![Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58491.jpg&w=3840&q=50)
Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain
Published on: August 8, 2019
PET/computed tomography shows association between subjective pain in knee joints and fluorine-18-fluorodeoxyglucose
Toshihiko Kamasaki1, Keisuke Mori1, Yasuyuki Taira1
1Department of Global Health, Medicine and Welfare.
Objective:
The aim of this study was to evaluate the capability of fluorine-18-fluorodeoxyglucose (F-FDG)-PET/computed tomography (CT) in screening for musculoskeletal inflammation and injury in the knee region.
Methods:
The study included 12 subjects (6 men and 6 women) who complained of knee pain at rest and 94 controls who did not. Maximum standardized uptake value (SUV)max was calculated for the right and left knees and compared via a 4-point numerical rating scale (NRS) for subjective knee pain. Correlations between SUV values were also evaluated.
Results:
SUVmax was significantly higher in knee joints with resting and/or walking pain than in pain-free knee joints. SUVmax in knee joints with walking pain were significantly correlated with NRS category (β = 0.129, P < 0.001).
Conclusion:
F-FDG-PET/CT may be useful in screening for musculoskeletal inflammation and injury in the knee region. As knee pain is common, especially among elderly individuals, we should consider conducting further examinations when F-FDG uptake is identified in knee joints.
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