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Updated: Jan 1, 2026
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Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection
Published on: December 30, 2025
1
Intrahepatic persistent fetal right umbilical vein: a retrospective study
Paolo Toscano1,2, Gabriele Saccone1,2, Lavinia Di Meglio1,2
1Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples "Federico II", Naples, Italy.
Summary
Persistent right umbilical vein (PRUV) is found in 0.38% of pregnancies. While often isolated, 23.3% of cases involve other fetal abnormalities, necessitating thorough prenatal evaluation.
Area of Science:
- Perinatology
- Fetal Medicine
- Medical Imaging
Background:
- Persistent right umbilical vein (PRUV) is a rare fetal anomaly.
- Understanding its incidence and associated risks is crucial for prenatal care.
Purpose of the Study:
- To determine the incidence of intrahepatic PRUV.
- To identify associated malformations in fetuses diagnosed with intrahepatic PRUV.
Main Methods:
- Single-center retrospective study.
- Reviewed records of women with prenatal diagnosis of intrahepatic PRUV.
- Included cases >13 weeks gestation, excluding situs abnormalities and extrahepatic PRUV.
Main Results:
- Intrahepatic PRUV incidence was 0.38% (219/57,079 cases).
- Mean gestational age at diagnosis was 21.8 weeks.
- 23.3% of cases had associated abnormalities, most commonly cardiovascular (8.7%).
Conclusions:
- Intrahepatic PRUV is frequently an isolated finding.
- Associated malformations occur in 23.3% of cases.
- Detailed fetal assessment, especially for cardiovascular anomalies, is recommended when PRUV is detected.
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