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Updated: Jan 1, 2026

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
Published on: July 4, 2011
Practical Applications of Biofluorescent Particle Counting in Environmental Monitoring Investigations
Aditya Prasad1, Annett Milling2, James Hauschild3
1AstraZeneca, Philadelphia, PA, USA.
Abstract:
Investigations into environmental monitoring (EM) excursions can be prolonged and do not always result in clear root causes or corrective and preventative actions. This article outlines how biofluorescent particle counting (BFPC) can be used in investigations to eliminate the inherent delays of culture-based methods. The application for investigations supplements routine EM, acting as a risk-reduction tool enabling real-time detection of viable microorganisms in air samples and supporting root cause analysis and remedial actions. The article includes guidance on how to use the technology, a real case study involving a mold excursion, and examples of business benefits achieved by various companies.
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