Hypertensive Urgency and Emergency in Alcohol Withdrawal: A Literature Review

Ermal Bojdani1,2,3,4, Anderson Chen2,3,4, Tina Zhang5

  • 1Harvard South Shore Psychiatry Residency Training Program, 940 Belmont St, Brockton, MA 02301. Bojdani2@gmail.com.

Insights

Hypertension can occur during alcohol detoxification, potentially leading to hypertensive urgency or emergency. Clinicians should monitor blood pressure and individualize treatment, considering patient comorbidities and potential end-organ damage.

Area of Science:

  • Internal Medicine
  • Cardiology
  • Addiction Medicine

Background:

  • Alcohol withdrawal syndrome (AWS) can manifest with significant physiological changes.
  • Hypertension is a common, though often transient, finding during AWS.
  • The risk of hypertensive urgency and emergency in AWS patients necessitates clinical vigilance.

Purpose of the Study:

  • To inform clinicians about the potential for hypertension, hypertensive urgency, and hypertensive emergency in patients undergoing alcohol detoxification.
  • To review diagnostic and treatment strategies for managing blood pressure in this specific patient population.

Main Methods:

  • A comprehensive literature search was conducted on PubMed using terms related to alcohol withdrawal and hypertension.
  • Studies were screened for relevance, with a focus on recent publications, and supplemented by expert-reviewed articles.
  • Searches for specific terms related to hypertensive urgency/emergency and treatment-resistant hypertension in AWS yielded limited results.

Main Results:

  • Hypertension during AWS is generally self-limiting but requires management to prevent severe complications.
  • Limited data exists on optimal hypertension management in AWS patients, often requiring individualized approaches.
  • Patients with pre-existing treatment-resistant hypertension may experience more challenging blood pressure control during withdrawal.

Conclusions:

  • Treatment for hypertension in AWS involves selecting medications based on side effect profiles and patient comorbidities.
  • Patients with suspected hypertensive urgency or emergency require thorough medical evaluation to assess for end-organ damage.
Abstract

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