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ICTV Virus Taxonomy Profile: Peribunyaviridae
Holly R Hughes1, Scott Adkins2, Sergey Alkhovskiy3
1Centers for Disease Control and Prevention, Fort Collins, CO, USA.
The Journal of General Virology
|December 18, 2019
Summary
Peribunyaviruses are enveloped RNA viruses transmitted by arthropods, causing diverse infections in vertebrates and humans. This summary details their taxonomy, transmission, and clinical significance.
Area of Science:
- Virology
- Arthropod-borne viruses
- RNA virus taxonomy
Background:
- Peribunyaviruses are enveloped viruses with segmented negative-sense RNA genomes.
- The family Peribunyaviridae encompasses genera like Orthobunyavirus, Herbevirus, Pacuvirus, and Shangavirus.
- Transmission involves arthropod vectors, often with vertebrate hosts, and can include transovarial routes.
Purpose of the Study:
- To summarize the International Committee on Taxonomy of Viruses (ICTV) report on Peribunyaviridae taxonomy.
- To outline the classification, characteristics, and transmission of peribunyaviruses.
- To highlight the clinical relevance of peribunyavirus infections.
Main Methods:
- Review of the ICTV Report on the taxonomy of the family Peribunyaviridae.
- Compilation of data on viral structure, genome, genera, and transmission cycles.
- Synthesis of information on host interactions and clinical outcomes.
Main Results:
- Peribunyaviruses possess three segmented single-stranded negative-sense RNA genomes.
- Global distribution with diverse genera and transmission patterns.
- Potential for segment reassortment and strain-specific clinical outcomes in humans and animals.
Conclusions:
- The ICTV provides a standardized classification for the family Peribunyaviridae.
- Understanding peribunyavirus biology is crucial for managing arthropod-borne diseases.
- Further research into peribunyavirus diversity and evolution is warranted.
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