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Development of Prodrugs for PDT-Based Combination Therapy Using a Singlet-Oxygen-Sensitive Linker and Quantitative

Luong Nguyen1, Mengjie Li1, Sukyung Woo1,2

  • 1Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73117, USA.

Journal of Clinical Medicine
|December 19, 2019
PubMed

Keywords:
Combretastatin A-4PDTSN-38aminoacrylatecombination therapylight-activatable prodrugspaclitaxelpharmacokineticsphotodynamic therapyphysiologically based pharmacokinetic modelingquantitative systems pharmacologysinglet-oxygen-sensitive linker

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