Related Experiment Video

Updated: Jan 1, 2026

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

5.7K

Systemic Immune-Inflammatory Index Predicts Clinical Outcomes for Elderly Patients with Acute Myocardial Infarction

Jiabao Huang1, Qing Zhang1, Runchang Wang1

  • 1Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland).

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|December 19, 2019
PubMed

Insights

The systemic immune-inflammatory index (SII) can predict outcomes in elderly patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). Higher SII scores indicate a worse prognosis for in-hospital and long-term survival and events.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Biomarkers

Background:

  • Acute myocardial infarction (AMI) poses significant risks for elderly patients.
  • Percutaneous coronary intervention (PCI) is a common treatment for AMI.
  • Prognostic markers are crucial for managing elderly AMI patients post-PCI.

Purpose of the Study:

  • To evaluate the systemic immune-inflammatory index (SII) as a prognostic tool.
  • To assess SII's utility in predicting in-hospital and long-term outcomes in elderly AMI patients undergoing PCI.

Main Methods:

  • Retrospective analysis of 711 elderly patients (65-85 years) with AMI treated with PCI.
  • Correlation analysis between SII and clinical outcomes using Cox regression and Kaplan-Meier methods.
  • Assessment of in-hospital and 3-year major adverse cardiovascular and cerebrovascular events (MACCE) and all-cause mortality.

Main Results:

  • Higher SII scores were associated with lower survival rates.
  • SII independently predicted in-hospital mortality (HR 3.32) and MACCE (HR 1.43).
  • SII also predicted long-term mortality (HR 1.95) and MACCE (HR 1.72) over 3 years.

Conclusions:

  • The systemic immune-inflammatory index (SII) is a readily available laboratory marker.
  • SII demonstrates independent predictive value for clinical endpoints in elderly AMI patients undergoing PCI.
  • SII can serve as a potential prognostic indicator for this patient group.

More Related Videos

An Intact Pericardium Ischemic Rodent Model07:15

An Intact Pericardium Ischemic Rodent Model

Published on: September 2, 2021

2.9K
Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.2K

Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
306
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
239
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
207
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
182
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
140
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
165