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Treatment of osteosarcoma.
1Department of Clinical Haematology and Oncology, Royal Children's Hospital, Melbourne, Victoria, Australia.
Clinical and Experimental Pharmacology & Physiology. Supplement
|January 1, 1979
Summary
Extreme diseases require extreme treatments, as seen with osteosarcoma. This paper reviews high-dose methotrexate treatment for osteosarcoma, sharing clinical experiences and other chemotherapy regimens.
Area of Science:
- Oncology
- Pharmacology
Background:
- Osteosarcoma is a rare bone cancer requiring aggressive treatment.
- High-dose methotrexate is an established chemotherapy regimen for osteosarcoma.
Purpose of the Study:
- To present the clinical experience of treating osteosarcoma with high-dose methotrexate.
- To summarize outcomes of various chemotherapy regimens for osteosarcoma.
Main Methods:
- Review of clinical data from the Department of Clinical Haematology and Oncology.
- Literature review of published experiences with chemotherapy for osteosarcoma.
Main Results:
- Clinical experience with high-dose methotrexate treatment for osteosarcoma is detailed.
- Comparative outcomes of different chemotherapy regimens are summarized.
Conclusions:
- High-dose methotrexate is a viable treatment for osteosarcoma.
- Further research into optimal chemotherapy strategies for osteosarcoma is warranted.