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Predictors of Preeclampsia Based on a 10-Year Case-Control Study
Arezoo Shayan1, Hadis Sourinejad2, Mansoureh Refaei1
1Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Preeclampsia risk is higher in older women, those with lower education, and blood group O. Fertilization during colder months also increases preeclampsia risk, aiding in identifying high-risk pregnancies.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Health
- Epidemiology
Background:
- Preeclampsia is a significant cause of maternal and fetal morbidity and mortality worldwide.
- Identifying predictive factors for preeclampsia is crucial for timely intervention and improved outcomes.
Purpose of the Study:
- To investigate predictors of preeclampsia.
- To identify risk factors associated with preeclampsia development.
Main Methods:
- Retrospective case-control study conducted over 10 years (2005-2015).
- Involved 729 preeclampsia cases and 729 controls.
- Data collected via hospital information system and questionnaires; analyzed using logistic regression.
Main Results:
- Advanced maternal age (OR=1.04) and lower educational attainment were associated with increased preeclampsia risk.
- Blood group O (compared to AB, B, A) and fertilization during autumn (compared to spring, summer) showed altered risk.
- Specific odds ratios (OR) were provided for different demographic and seasonal factors.
Conclusions:
- High age, low education, blood group O, and fertilization in colder seasons are potential risk factors for preeclampsia.
- Understanding these risk factors can aid in identifying high-risk individuals and designing targeted interventions.
- Further research may validate these findings and inform clinical practice for preeclampsia prevention.
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