Related Experiment Video
Updated: Aug 18, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
Reflux as an etiological factor of carcinoma of the laryngopharynx
1Department of Surgery/Head and Neck (Otolaryngology), UCLA School of Medicine 90024-1624.
Abstract:
This study examined charts and 16-mm pictures or videotapes of 138 patients with carcinoma of the larynx treated during the last 10 years. Among these patients, 19 were nonsmokers and nondrinkers or only light social drinkers with moderate to severe gastroesophageal reflux (GER). Serial cinephotographs are presented with follow-up of up to 10 years. The common presence of GER in these nonsmoking, nondrinking patients and the probable role of this chronic irritative disorder as a causative agent in carcinoma of the laryngopharynx are discussed.
Related Concept Videos
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Achalasia
Gastroesophageal Reflux Disease
Gastritis II: Pathophysiology

