Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Type II collagen distribution in rodents.

T J Yoo¹, K Tomoda

¹Department of Medicine, University of Tennessee-Memphis 38163.

The Laryngoscope

|November 1, 1988

Summary

Type II collagen, crucial for cartilage, is widely distributed throughout animal ear structures. This study maps its presence in the auricle, auditory canal, middle ear, and inner ear, aiding in understanding ear development and disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Indications for partial parotidectomy using retrograde dissection of the marginal mandibular branch of the facial nerve for benign tumours of the parotid gland.

The British journal of oral & maxillofacial surgery·2018

Same author

The paracrine effect of mesenchymal human stem cells restored hearing in β-tubulin induced autoimmune sensorineural hearing loss.

Hearing research·2015

Same author

Combined treatment with cyclophosphamide and prednisolone is effective for secondary amyloidosis with SAA1γ/γ genotype in a patient with rheumatoid arthritis.

Modern rheumatology·2014

Same author

Assessment of the AAV-mediated expression of channelrhodopsin-2 and halorhodopsin in brainstem neurons mediating auditory signaling.

Brain research·2012

Same author

Evaluation of postoperative function in patients undergoing reconstruction following resection of superior and lateral oropharyngeal cancer: long-term outcomes of reconstruction with the Gehanno method.

International journal of oral and maxillofacial surgery·2011

Same author

Prevention and treatment of DNA vaccine encoding cockroach allergen Bla g 1 in a mouse model of allergic airway inflammation.

Allergy·2011

Area of Science:

Histology
Biochemistry
Otolaryngology

Background:

Type II collagen is a major structural protein in cartilage.
Its specific distribution in the complex anatomy of the animal ear is not fully elucidated.
Understanding collagen distribution is vital for ear development and pathology research.

Purpose of the Study:

To precisely map the anatomical distribution of type II collagen within the animal ear.
To utilize advanced immunohistochemical techniques for accurate localization.
To provide a detailed reference for future studies on ear biomechanics and diseases.

Main Methods:

Immunohistochemical analysis using specific monoclonal antibodies against type II collagen.
Systematic examination of various anatomical regions of the animal ear.
Microscopic visualization and documentation of positive staining for type II collagen.

Main Results:

Type II collagen was detected in numerous ear structures, including the auricle, external auditory meatus, tympanic membrane, ossicles, Eustachian tube, and otic capsule.
Specific inner ear components like the spiral ligament, tectorial membrane, and vestibular sensory epithelia also showed type II collagen presence.
The study provides a comprehensive atlas of type II collagen localization in the animal ear.

Conclusions:

Type II collagen is extensively distributed throughout the cartilage and connective tissues of the animal ear.
This widespread presence suggests its critical role in maintaining the structural integrity and function of diverse ear components.
The findings offer a foundational dataset for investigating type II collagen-related disorders affecting hearing and balance.

Related Experiment Videos