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Mycobacterium tuberculosis and Pseudoramibacter alactolyticus coinfection in brain after dental extraction: A case
Yixin Liao1, Fan Wu2, Fahui Dai2
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha.
Introduction:
More than 1200 different types of microbes were found in the human mouth, only some of these microorganisms were associated with intracranial bacterial infection. However, there are limited data available about the Pseudoramibacter alactolyticus (P alactolyticus) or Mycobacterium tuberculosis (MTB) intracranial infections oral origin.
Patient Concerns:
Here, we reported a rarely case with P alactolyticus and MTB coinfection in central nervous after dental extraction. The 44-year-old man presented with progressive headache over the last 2 weeks and a sustained fever >39°C, with a dental extraction performed 2 days before the onset of headache.
Diagnosis:
P alactolyticus and MTB were confirmed by real-time polymerase chain reaction targeting the16S ribosomal RNA gene. The presence of MTB was also demonstrated by positive acid-fast staining of the purulent discharge.
Interventions:
The patient was treated by metronidazole and anti-TB treatment OUTCOMES:: The patient fully recovered without sequela.
Conclusion:
In conclusion there should be awareness of the possibility of P alactolyticus or MTB intracranial infections following tooth extraction.
Insights
Intracranial infections from Pseudoramibacter alactolyticus (P alactolyticus) or Mycobacterium tuberculosis (MTB) following dental procedures are rare but possible. Early diagnosis and treatment led to a full recovery in a coinfection case.
Area of Science:
- Oral microbiology
- Infectious diseases
- Neurology
Background:
- The human mouth harbors over 1200 microbial types, with some linked to intracranial bacterial infections.
- Limited data exists on oral origins of intracranial infections caused by Pseudoramibacter alactolyticus (P alactolyticus) or Mycobacterium tuberculosis (MTB).
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