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Cellular angiofibroma in the hypopharynx: A case report.
Ya Liu1, Yaping Xu, Qinying Wang
1Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Medicine
|December 20, 2019
Summary
This study reports the first case of cellular angiofibroma in the hypopharynx, a rare benign tumor. Surgical excision was successful, with no recurrence observed six months post-operation.
Area of Science:
- Head and Neck Surgery
- Pathology
- Oncology
Background:
- Cellular angiofibroma is a rare benign mesenchymal tumor typically found in the genital region.
- Its occurrence in the head and neck, particularly the hypopharynx, is exceptionally rare.
Observation:
- A 54-year-old male presented with a gradually enlarging throat mass.
- Laryngoscopy and MRI revealed a tumor on the right lateral pharyngeal wall.
- Initial assessment suggested a benign pharyngeal tumor.
Findings:
- Immunohistochemical analysis confirmed the diagnosis of cellular angiofibroma.
- The tumor was successfully resected via surgical excision under general anesthesia.
Implications:
- This case highlights the possibility of cellular angiofibroma in the hypopharynx, necessitating consideration in differential diagnoses.
- Immunohistochemistry is crucial for accurate diagnosis of this rare entity.
- Local excision followed by follow-up is an effective treatment strategy with good prognosis.

