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Development of Type 2 Innate Lymphoid Cells Is Selectively Inhibited by Sustained E Protein Activity

Hannah Berrett1,2, Liangyue Qian1, Olga Roman1

  • 1Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104; and.

Immunohorizons
|December 20, 2019
PubMed
Summary

Small increases in E protein activity selectively inhibit type 2 innate lymphoid cells (ILCs) development. This finding reveals how modulating E protein activity can bias ILC subset cell fate decisions during development.

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