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Updated: Jan 1, 2026
Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
Published on: March 29, 2022
Association between serum 25-hydroxyvitamin D levels and myopia in general Korean adults
1Department of Ophthalmology, Apgujung St. Mary's Eye Center, Seoul, Korea.
Purpose:
We performed this study to determine the association between serum 25-hydroxyvitamin D [25(OH) D] level and myopia in adults.
Methods:
A total of 25,199 subjects aged ≥20 years were included from the National Health and Nutrition Examination Survey 2008-2012. Blood 25(OH)D levels were evaluated from blood samples. Refractive error was measured without cycloplegia. Myopia and high myopia were defined as ≥-0.50 diopters (D) and ≥-6.0 D, respectively. Other covariates such as education, physical activity, and economic status were obtained from interviews.
Results:
Linear regression analysis showed that as 25(OH) D level increased by 1 ng/mL, myopic refractive error significantly decreased by 0.01 D (P < 0.001) after adjusting for potential confounders including sex, age, height, education level, economic status, physical activity, and sunlight exposure time. The odds ratios for myopia was 0.75 (95% Confidence interval [CI]; 0.67-0.84, P < 0.001) in the highest 25(OH) D quintile compared to the lowest quintile. The odds ratios for high myopia was 0.63 (95% CI; 0.47-0.85, P < 0.001) in the highest 25(OH)D quintile compared to the lowest quintile.
Conclusion:
: Serum 25(OH)D level was inversely associated with myopia in Korean adults.
