Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

Modeling in Therapy

Modeling in Therapy

Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The complete mitochondrial genome of <i>Cornus officinalis</i> reveals a multipartite structure and clarifies its phylogenetic position.

Mitochondrial DNA. Part B, Resources·2026

Same author

A Reference Assembly for the Legume Cover Crop Smooth Vetch <i>Vicia villosa</i> Roth var. <i>glabrescens</i>.

Biology·2026

Same author

Deciphering the single-cell transcriptomic atlas of donkey (Equus asinus) gonad development in early gestation.

Developmental biology·2026

Same author

Evaluation of a Cell-Based Potency Assay for Detection of the Potency of TrenibotulinumtoxinE<sup>®</sup> (TrenibotE).

Toxins·2026

Same author

Anti-Corrosion Interfacial Design for Aqueous Zn Metal Batteries with Enhanced Calendar Life.

Nano letters·2026

Same author

A diagnostic model for NTM disease in HIV-positive patients: a machine learning-based analysis with novel inflammatory markers.

Frontiers in immunology·2025

Search research articles

Related Experiment Video

Updated: Jan 1, 2026

Strategies for Assessing Autistic-Like Behaviors in Mice

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Biomarkers in autism spectrum disorders: Current progress.

Liming Shen¹, XuKun Liu¹, Huajie Zhang¹

¹College of Life Science and Oceanography, Shenzhen University, Shenzhen 518060, PR China.

Clinica Chimica Acta; International Journal of Clinical Chemistry

|December 21, 2019

Summary

Researchers are exploring genes, proteins, and metabolites as potential diagnostic biomarkers for autism spectrum disorder (ASD). Early interventions improve symptoms, but reliable biomarkers are needed for diagnosis and understanding ASD pathogenesis.

Keywords:

Autism spectrum disorder Biomarker Genetic testing Metabolomics Proteomics

More Related Videos

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

Related Experiment Videos

Last Updated: Jan 1, 2026

Strategies for Assessing Autistic-Like Behaviors in Mice

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers

Published on: March 14, 2018

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

Area of Science:

Neuroscience
Genetics
Biochemistry

Background:

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with unknown etiology and pathogenesis.
Current diagnostic methods lack specific biomarkers, necessitating further research.
Early behavioral interventions show promise in managing ASD symptoms.

Purpose of the Study:

To review recent findings on potential diagnostic biomarkers for ASD.
To explore the role of genes, proteins, peptides, and metabolites in ASD diagnosis and pathogenesis.
To discuss the application of various analytical techniques in identifying these biomarkers.

Main Methods:

Review of current scientific literature on ASD biomarkers.
Analysis of genetic testing, proteomic, metabolomic, and transcriptomic data.
Examination of studies focusing on specific proteins, metabolites, immune disturbances, and cytokines.

Main Results:

Progress has been made in identifying potential diagnostic markers for ASD across different molecular levels.
Genes, proteins, peptides, and metabolites show promise as indicators for ASD.
Transcriptomic analysis, immune markers, and cytokines are also being investigated.

Conclusions:

No definitive diagnostic markers for ASD have been identified yet.
Continued research into genetic, proteomic, and metabolomic profiles is crucial for developing reliable ASD biomarkers.
Understanding the pathogenesis involving these molecular factors is key to advancing ASD diagnosis and treatment.