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Author Correction: An in vitro assay and artificial intelligence approach to determine rate constants of

Edward Price1,2, Andre J Gesquiere3,4,5,6

  • 1NanoScience Technology Center, University of Central Florida, Orlando, FL, 32826, USA.

Scientific Reports
|December 21, 2019
PubMed

Keywords:
nanomaterial toxicitycell interaction modelingAI in toxicologyin vitro assays

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Patch Clamp01:18

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Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...