Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viruses with RNA Genomes01:29

Viruses with RNA Genomes

648
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
648
Viral Structure00:56

Viral Structure

73.6K
Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
73.6K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

1.6K
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Capsid and integrase play essential apposing roles in viral ribonucleoprotein assembly during HIV-1 core morphogenesis.

iScience·2026
Same author

The host protein cyclophilin A restricts nuclear entry of HIV-1 mutants by reducing the elasticity of the viral capsid.

PLoS pathogens·2026
Same author

A Hybrid Gag Lattice as a Structural Intermediate in HIV-1 Maturation.

bioRxiv : the preprint server for biology·2026
Same author

Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat.

Journal of the American Chemical Society·2025
Same author

The host protein cyclophilin A inhibits HIV-1 nuclear entry by decreasing capsid elasticity.

bioRxiv : the preprint server for biology·2025
Same author

HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability.

Nature microbiology·2025
Same journal

The penicillin-binding protein PBP1b fortifies the Escherichia coli division site against osmotic rupture.

Nature microbiology·2026
Same journal

Identification of chemical features for improved outer membrane permeation in mycobacteria using machine learning.

Nature microbiology·2026
Same journal

Author Correction: Gut commensal Christensenella minuta modulates host metabolism via acylated secondary bile acids.

Nature microbiology·2026
Same journal

Mobile genetic elements shape microbial diversity and functions in thawing permafrost soils.

Nature microbiology·2026
Same journal

Epistatic interactions inform rational design of synthetic microbial communities for bioremediation.

Nature microbiology·2026
Same journal

END nucleases are antiphage defence systems targeting multiple phages with modified genomes.

Nature microbiology·2026
See all related articles

Related Experiment Video

Updated: Jan 1, 2026

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors
08:33

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Published on: January 19, 2015

9.2K

Shielding the HIV-1 capsid

Christopher Aiken1

  • 1Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA. chris.aiken@vumc.org.

Nature Microbiology
|December 21, 2019
PubMed
Summary

No abstract available in PubMed .

More Related Videos

In vitro Uncoating of HIV-1 Cores
10:49

In vitro Uncoating of HIV-1 Cores

Published on: November 8, 2011

16.1K
Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.8K

Related Experiment Videos

Last Updated: Jan 1, 2026

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors
08:33

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Published on: January 19, 2015

9.2K
In vitro Uncoating of HIV-1 Cores
10:49

In vitro Uncoating of HIV-1 Cores

Published on: November 8, 2011

16.1K
Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.8K