Case report: Albendazole associated psychosis

Area of Science:

• Neuroscience
• Pharmacology
• Toxicology

Background:

• The link between albendazole monotherapy and psychosis is not well-documented in existing medical literature.
• Albendazole is a widely used antiparasitic medication.

Observation:

• A patient developed acute psychosis during albendazole treatment.
• Psychosis symptoms resolved after albendazole was stopped and aripiprazole was initiated.

Findings:

• The temporal association and available data strongly suggest albendazole induced the psychotic reaction.
• This adverse event highlights a potential neurotoxicity of albendazole.

Implications:

• Healthcare providers should consider the risk of psychosis when prescribing albendazole.
• Awareness of this rare but severe adverse effect is crucial for patient safety and management.