Double Rule In: Concomitant Acute Coronary Occlusion and Pulmonary Embolism
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Updated: Jan 1, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Valmiki Maharaj1, Pratik S Velangi1, Kurt Prins1
1Division of Cardiology, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.
Insights
Computed tomography angiography (CTA) is common for ruling out coronary artery disease and pulmonary embolism in emergency patients. However, finding both acute coronary occlusion and pulmonary embolism on the same CTA scan is very rare.
Area of Science:
- Cardiovascular Imaging
- Emergency Medicine
- Radiology
Background:
- Computed tomography angiography (CTA) is a key diagnostic tool in emergency departments for patients with acute chest pain.
- CTA is routinely used to exclude obstructive coronary artery disease (CAD) and pulmonary embolism (PE).
Purpose of the Study:
- To highlight the rarity of diagnosing concomitant acute coronary occlusion and pulmonary embolism on a single CTA scan.
- To emphasize the diagnostic challenges and implications of identifying these two critical conditions simultaneously.
Main Methods:
- Review of computed tomography angiography (CTA) scans in emergency department patients presenting with acute chest pain.
- Analysis of cases where both acute coronary occlusion and pulmonary embolism were identified concurrently.
Main Results:
- Computed tomography angiography (CTA) is frequently employed for the "double rule out" of coronary artery disease and pulmonary embolism.
- The simultaneous diagnosis of acute coronary occlusion and pulmonary embolism on a single CTA scan is an exceptionally uncommon finding.
Conclusions:
- While CTA is effective for evaluating acute chest pain, the co-occurrence of acute coronary occlusion and pulmonary embolism is a rare diagnostic scenario.
- Clinicians should be aware of this rare possibility, although it is seldom encountered in routine practice.
Abstract:
Computed tomography angiography is frequently used for double rule out of obstructive coronary artery disease and pulmonary embolism in patients presenting to the emergency department with acute chest pain, but it is rare to see concomitant acute coronary occlusion and pulmonary embolism on the same computed tomography angiography scan.
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