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Published on: June 14, 2020
Varicella zoster virus (VZV) oculomeningoencephalomyeloradiculitis: a previously undescribed constellation
Etsegenet F Tizazu1, Gina Chang2, Joseph R Berger2
1Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Gates 3W, Philadelphia, PA, 19104, USA. etsegenet.tizazu@pennmedicine.upenn.edu.
Abstract:
A 53-year-old immunocompromised woman developed acute left eye blindness and paraparesis suspected to be due to neuromyelitis optica (NMO). During treatment for NMO, right eye blindness and progressive multiple cranial neuropathies developed. Cerebrospinal fluid polymerase chain reaction (PCR) revealed Varicella zoster virus (VZV). This case emphasizes the importance of considering VZV in individuals, particularly the immunocompromised, presenting with a constellation of neurological signs and symptoms, even in the absence of rash.
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