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Updated: Jan 1, 2026

Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity
Published on: January 6, 2015
Clinical Application of Pulmonary Function Testing in Small Animals
Anusha Balakrishnan1, Carissa W Tong2
1Emergency and Critical Care, Cornell University Veterinary Specialists, 880 Canal Street, Stamford, CT 06902, USA; Emergency and Critical Care, Cornell University College of Veterinary Medicine, Ithaca, NY, USA.
Abstract:
Pulmonary function tests (PFTs) are important diagnostic tools that have wide clinical applications in human and veterinary medicine. Widespread use of PFTs in measuring lung volumes in veterinary medicine was historically limited by the need for specialized equipment to accurately perform and interpret these tests, and by lack of patient cooperation. However, recent advances and modifications have allowed PFTs to be safely performed in conscious veterinary patients with minimal stress. This article focuses on the most commonly used tests of pulmonary function including tests of pulmonary mechanics and of gas exchange in the lungs.

