Related Experiment Video
Updated: Jan 1, 2026

Postoperative Ileus Murine Model
Published on: July 12, 2024
The Use of Coffee to Decrease the Incidence of Postoperative Ileus: A Systematic Review and Meta-Analysis
Terri D Kane1, Tito D Tubog1, James R Schmidt1
1Graduate Programs of Nurse Anesthesia, Texas Wesleyan University, Fort Worth, TX.
Purpose:
To investigate the efficacy of providing coffee to elective abdominal surgery patients, immediately postoperatively, to lessen postoperative ileus.
Design:
A systematic review with meta-analysis of six randomized controlled trials published since 2012.
Methods:
Methodological quality was evaluated using the Cochrane guidelines. The Grading of Recommendations, Assessment, Development, and Evaluations assessment tool evaluated the quality of the evidence. Subgroup analyses were completed if the I2 statistic demonstrated heterogeneity (greater than 50%).
Findings:
Coffee was statistically significant in shortening the time between surgery and the first passage of stool (mean difference, -9.38; 95% confidence interval, -17.60 to -1.16; P = .03). Although not statistically significant (P = .20), the overall effect favored shorter hospital stays for those patients receiving coffee.
Conclusions:
The current systematic review and meta-analysis suggests that coffee given as early as 2 hours postoperatively decreases time to first bowel movement. In addition, patients tolerated solid food faster and were discharged sooner when given coffee immediately postoperatively.
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