Related Experiment Video

Updated: Jan 1, 2026

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

14.1K

[Inappropriate antifungal prescription and the need for antifungal stewardship programs]

Juan Pablo Osorio-Lombana1, Sonia Isabel Cuervo-Maldonado1, María José López-Mora2

  • 1Facultad de Medicina, Universidad Nacional de Colombia, Colombia.

Revista Chilena De Infectologia : Organo Oficial De La Sociedad Chilena De Infectologia
|December 21, 2019
PubMed

Insights

Invasive fungal disease (IFD) is rising in at-risk patients, leading to increased antifungal use. Antifungal stewardship programs can optimize prescribing, reducing costs and side effects.

Area of Science:

  • Infectious Diseases
  • Clinical Pharmacy
  • Healthcare Management

Background:

  • Invasive fungal disease (IFD) incidence is increasing in immunocompromised and critically ill populations.
  • This rise necessitates greater use of antifungal agents for prophylaxis, pre-emptive, and empiric treatments.
  • Suboptimal antifungal prescribing, with up to 72% inappropriate formulations, leads to adverse effects, drug interactions, and increased healthcare costs.

Purpose of the Study:

  • To review the literature on the appropriate use of antifungal agents.
  • To present the experiences of centers that have implemented antifungal stewardship programs.
  • To highlight the benefits of antifungal stewardship in optimizing antifungal therapy.

Main Methods:

  • A narrative review of published scientific literature was conducted.
  • The review focused on articles addressing appropriate antifungal agent use.
  • Case studies and experiences from antifungal stewardship program implementation were analyzed.

Main Results:

  • Inappropriate antifungal formulations are common, impacting patient safety and costs.
  • Antifungal stewardship strategies, analogous to antimicrobial stewardship, are effective.
  • Implementation of antifungal stewardship programs has shown positive outcomes in various centers.

Conclusions:

  • Antifungal stewardship is crucial for rationalizing antifungal prescribing.
  • Optimized antifungal use improves patient outcomes and reduces healthcare expenditure.
  • Widespread adoption of antifungal stewardship programs is recommended.

More Related Videos

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

7.3K
An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

5.7K

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
173
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
1.1K
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
219
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
187
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
349
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K