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Simultaneous intussusception associated with adenovirus infection in monozygotic twins: A case report
Yu-Hsien Lee1, Lung-Huang Lin1,2, Shin-Pin Hung1,2
1Department of Pediatrics, Cathay General Hospital, Taipei City.
Insights
Adenovirus infection may cause intussusception in children. This case study highlights twins with simultaneous intussusception and adenovirus, suggesting a link between viral infection and this intestinal obstruction.
Area of Science:
- Pediatric Gastroenterology
- Viral Infections in Children
- Gastrointestinal Disorders
Background:
- Intussusception is a frequent cause of intestinal obstruction in pediatric patients.
- Medical reduction is the standard treatment for intussusception.
- The etiology of intussusception is often idiopathic, but infectious agents are suspected.
- Adenovirus is a common viral pathogen in children.
Rationale:
Intussusception, a common cause of intestinal obstruction in children, typically requires medical reduction. Here, we describe the case of a pair of twins who had simultaneous intussusception and were positive for fecal adenovirus-strongly indicating that adenovirus infection may be a main cause of the intussusception.
Patient Concerns:
Two 1-year-old twin girls were brought to Cathay General Hospital one after another on the same day. Both presented with intermittent abdominal pain, abdominal distension, diarrhea, and loss of appetite.
Diagnoses:
Their laboratory data were adenovirus positivity in rectal swab culture. Intussusception was diagnosed through a lower gastrointestinal series.
Interventions:
The twins were treated with reduction for intussusception.
Outcomes:
Both patients recovered well, without recurrence.
Lessons:
Most cases of intussusception are idiopathic. However, some potential risk factors-as strongly suggested by the current cases-are genetic factors and adenovirus infection.
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