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Related Experiment Video

Updated: Jan 1, 2026

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
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Gait Asymmetry Post-Stroke: Determining Valid and Reliable Methods Using a Single Accelerometer Located on the Trunk.

Christopher Buckley1, M Encarna Micó-Amigo1, Michael Dunne-Willows2

  • 1Institute of Neuroscience/Institute for Ageing, Newcastle University, Newcastle Upon Tyne NE4 5PL, UK.

Sensors (Basel, Switzerland)
|December 22, 2019
PubMed
Summary

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Step regularity from vertical accelerometer signals is a valid and reliable measure of gait asymmetry in stroke survivors. This digital biomarker shows promise for tracking recovery and rehabilitation progress.

Area of Science:

  • Biomedical Engineering
  • Rehabilitation Science
  • Neurology

Background:

  • Gait asymmetry is a primary impairment following stroke, significantly impacting mobility and recovery.
  • Accelerometers offer a feasible method for quantifying digital gait variables, including asymmetry.
  • A lack of consensus exists on the most valid and reliable accelerometer-derived metrics for gait asymmetry.

Purpose of the Study:

  • To compare the validity and reliability of various acceleration-derived gait asymmetry variables.
  • To identify the most accurate digital biomarker for measuring gait asymmetry post-stroke.

Main Methods:

  • Twenty-five stroke participants underwent repeated walking trials over an instrumented walkway (GaitRite) while wearing a tri-axial accelerometer.
  • Multiple asymmetry variables (harmonic ratio, autocorrelation, gait symmetry index, phase plots, acceleration, jerk RMS) were calculated from accelerometer data.
Keywords:
accelerometerasymmetrygaitreliabilitystroketrunkvalidity

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  • Concurrent validity was assessed against GaitRite, and test-retest reliability was evaluated over one week.

    • Main Results:

    • Step regularity derived from the vertical accelerometer signal demonstrated the strongest concurrent validity.
    • This metric also exhibited excellent test-retest reliability (rho = 0.87, ICC21 = 0.98).

    Conclusions:

    • Step regularity from vertical accelerometer signals is a highly reliable and valid digital biomarker for quantifying gait asymmetry in post-stroke individuals.
    • Further research is warranted to evaluate its responsiveness to change during recovery and rehabilitation for potential use as a digital biomarker.