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Pregnancy after mumps: a case report.

Parviz Shahabi1, Shiva Asadzadeh1, Hossein Bannazadeh Baghi2,3

  • 1Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

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|December 23, 2019
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Summary

Mumps-induced oophoritis can cause infertility. A woman with an infantile uterus and atrophic ovaries due to childhood mumps successfully achieved pregnancy after hormonal treatments stimulated uterine growth.

Keywords:
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Area of Science:

  • Reproductive Endocrinology
  • Gynecology

Background:

  • Oophoritis, a complication of mumps, affects a small percentage of postpubertal women.
  • Presents a case of infertility and amenorrhea in a 31-year-old Iranian woman due to childhood mumps-induced oophoritis, infantile uterus, and atrophic ovaries.

Observation:

  • The patient was diagnosed with oophoritis at age 8 and experienced amenorrhea.
  • She underwent low-dose contraceptive treatment from age 19 to 31, showing slow uterine growth.
  • At 31, a 3-month course of Drospil (drospirenone/ethinyl estradiol) induced significant uterine growth and menses.

Findings:

  • Hormonal therapy, including low-dose contraceptives and Drospil, demonstrated a synergistic effect on uterine growth.
  • The patient achieved a successful pregnancy via assisted reproductive technology using a donor oocyte.

Implications:

  • This case highlights a potential therapeutic approach for uterine development in cases of infertility secondary to oophoritis.
  • Hormonal stimulation can promote uterine growth, enabling pregnancy in women with previously underdeveloped uteri.