Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Autoimmune Disorders01:29

Autoimmune Disorders

1.4K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
1.4K
Accessory Structures of the Skin: Hair Growth and Types01:20

Accessory Structures of the Skin: Hair Growth and Types

2.2K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
2.2K
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

2.8K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
2.8K
Accessory Structures of the Skin: Hair and Hair Follicles01:16

Accessory Structures of the Skin: Hair and Hair Follicles

4.1K
Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
4.1K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical Technique and Oro-Nasal Fistula Formation After Primary Palatoplasty: A Comparative Study of Closed Intravelar and Modified Veau-Wardill-Kilner Techniques.

Journal of clinical medicine·2026
Same author

Vascular Proliferation in Biopsies from Active Lichen Planopilaris as a Novel Pathologic Finding.

The American Journal of dermatopathology·2026
Same author

Exploring the Potential Link Between Minoxidil Use and Rosacea Using A Real-World Data Base.

Journal of drugs in dermatology : JDD·2026
Same author

Biopsy from the epicenter of the scalp whorl diagnoses early lichen planopilaris.

Journal of the American Academy of Dermatology·2025
Same author

Merkel cell carcinoma with synchronous but spatially distinct squamous cell carcinoma of the head: Case report of differing PRAME expression and response to checkpoint inhibitor therapy.

JAAD case reports·2025
Same author

Enhancing Patient Satisfaction and Quality of Life With Mohs Micrographic Surgery: A Systematic Review of Patient Education, Communication, and Anxiety Management.

Cutis·2025

Related Experiment Video

Updated: Jan 1, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.3K

Alopecia as a systemic disease.

Sonali Nanda1, Valeria De Bedout1, Mariya Miteva1

  • 1Dr. Philip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

Clinics in Dermatology
|December 23, 2019
PubMed
Summary
This summary is machine-generated.

Alopecia, a hair loss condition, can be primary or secondary to systemic issues. Diagnosis involves trichoscopy and histopathology, with treatment focusing on the underlying cause.

More Related Videos

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.5K
Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.8K

Related Experiment Videos

Last Updated: Jan 1, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.3K
Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.5K
Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.8K

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Alopecia significantly impacts social and psychological well-being.
  • Primary alopecia affects hair follicles without systemic involvement.
  • Secondary alopecia results from systemic diseases, medications, or trauma.

Purpose of the Study:

  • To review the diagnosis and management of secondary alopecia.
  • To highlight the role of trichoscopy and histopathology in diagnosis.
  • To discuss systemic conditions associated with secondary alopecia.

Main Methods:

  • Review of systemic diseases causing secondary alopecia (connective tissue, granulomatous, bullous, infections, tumors).
  • Emphasis on trichoscopy as a non-invasive diagnostic tool.
  • Discussion of histopathology for definitive diagnosis via scalp biopsy.

Main Results:

  • Secondary alopecia is linked to various systemic conditions.
  • Trichoscopy aids in clinical diagnosis and biopsy site selection.
  • Histopathology provides the definitive diagnosis for most secondary alopecia cases.

Conclusions:

  • Treating the underlying systemic condition is paramount for managing secondary alopecia.
  • Topical treatments can supplement management strategies.
  • Accurate diagnosis through trichoscopy and histopathology is crucial.