Advanced sensing platform for electrochemical monitoring of the environmental toxin; bisphenol A

Environmental xenoestrogen, Bisphenol A (BPA), is a vitally important industrial raw chemical which can bring about a wide variety of adverse impacts on our health and environment. Therefore, it is imperative to develop efficacious systems to measure BPA and improve the life quality. Herein, a mixture of titanium dioxide nanoparticles (TiO₂NPs) and glutaraldehyde cross-linked chitosan (GA-CS) loaded into a carbon nanotubes paste matrix to construct a novel electrochemical sensor (TiO₂NPs/GA-CS/CNTPE) with a synergetic intensified current signal for the quantitative analysis of BPA. The surface morphology of the modified sensor was assessed by field emission scanning electron microscope (FESEM), X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDX). The prepared TiO2NPs/GA-CS/CNTPE displayed increased electrocatalytic activity toward BPA. The calibration curve of BPA shows linear response in the BPA concentration range of 0.01-6 μM with the lowest limit of detection of 9.58 nM (S/N = 3). The sensor exhibited high sensitivity and selectivity, good reproducibility, desirable stability and excellent performance in detection of BPA in real samples, which prove that TiO2NPs/GA-CS/CNTPE is quite applicable for food, medical and environmental analyses.