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Related Concept Videos

Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

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The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
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Pleura of the Lungs01:13

Pleura of the Lungs

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

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Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
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Pneumothorax-II01:27

Pneumothorax-II

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Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
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Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

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Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Related Experiment Video

Updated: Jan 1, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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Malignant Pleural PEComa: A Previously Undocumented Site.

Rebecca Tian Mei Au1, Aneez D B Ahmed2, Bernard Chi Shen Ho1

  • 1Department of Pathology, Tan Tock Seng Hospital, Singapore.

International Journal of Surgical Pathology
|December 24, 2019
PubMed
Summary

Malignant PEComa, a rare mesenchymal tumor, can arise in the pleura. This case study details a unique instance in a 43-year-old woman, discussing its pathology and differential diagnoses.

Keywords:
PEComadifferential diagnosesmalignantpleura

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Related Experiment Videos

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Area of Science:

  • Oncology
  • Pathology
  • Mesenchymal Tumors

Background:

  • Perivascular epithelioid cell (PEC) tumors are uncommon mesenchymal neoplasms.
  • These tumors can occur in various anatomical locations.
  • While often benign, malignant variants of PEC tumors are known to exist.

Observation:

  • This report details the first documented case of a malignant PEComa originating in the pleura.
  • The affected individual was a 43-year-old Malay woman.

Findings:

  • The study focuses on the pathological characteristics of this rare pleural malignant PEComa.
  • Differential diagnoses for this specific tumor presentation are explored.

Implications:

  • This case expands the known anatomical sites for malignant PEComa.
  • Understanding the pathology and differential diagnosis is crucial for accurate diagnosis and patient management.
  • Highlights the importance of considering rare mesenchymal tumors in pleural pathology.