Related Experiment Video
Updated: Jan 1, 2026

Preparing Lamellae from Vitreous Biological Samples Using a Dual-Beam Scanning Electron Microscope for Cryo-Electron Tomography
Published on: August 5, 2021
Hardly Vacuous: The Parasitophorous Vacuolar Membrane of Malaria Parasites
Daniel E Goldberg1, Joshua Zimmerberg2
1Departments of Medicine and Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA.
Abstract:
When a malaria parasite invades a host erythrocyte it pushes itself in and invaginates a portion of the host membrane, thereby sealing itself inside and establishing itself in the resulting vacuole. The parasitophorous vacuolar membrane (PVM) that surrounds the parasite is modified by the parasite, using its secretory organelles. To survive within this enveloping membrane, the organism must take in nutrients, secrete wastes, export proteins into the host cell, and eventually egress. Here, we review current understanding of the unique solutions Plasmodium has evolved to these challenges and discuss the remaining questions.
More Related Videos
05:28Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors
Published on: May 12, 2022
09:13Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
Published on: November 22, 2024
Related Concept Videos
Symbiosis
Diversity of Protists II
Diversity of Protists I
Intralumenal Vesicles and Multivesicular Bodies
Diversity of Protists IV
Overview of Protists