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Low Risk of Procedure Related Major Amputation Following Revascularisation for Intermittent Claudication: A

Henrik Djerf1, Jonas Hellman2, Erik Baubeta Fridh3

  • 1Department of Vascular Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden; Institute of Clinical Science, Department of Radiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
|December 24, 2019
PubMed

Insights

Revascularization for intermittent claudication (IC) carries a low risk of major amputation. This study found a 0.2% rate of procedure-related amputation within one year for IC patients.

Area of Science:

  • Vascular surgery
  • Epidemiology
  • Patient outcomes

Background:

  • Intermittent claudication (IC) is a common symptom of peripheral artery disease.
  • Revascularization procedures aim to restore blood flow but may carry risks.
  • Understanding procedure-related amputation risk is crucial for patient management.

Purpose of the Study:

  • To determine the incidence of major amputation directly related to lower limb revascularization for IC.
  • To assess this risk within a population-based cohort in Sweden.

Main Methods:

  • Observational cohort study using Swedish national registries (Swedvasc, National Patient Registry).
  • Identified 5,860 patients undergoing open or endovascular revascularization for IC (2008-2012).
  • Defined procedure-related amputation as ipsilateral amputation within one year post-revascularization, with medical record review for accuracy.

Main Results:

  • A total of 5,860 patients were revascularized for IC.
  • 9 out of 5,860 patients (0.2%) underwent ipsilateral major amputation within one year.
  • Exclusions and misclassifications were carefully addressed, with 27 amputations occurring beyond one year.

Conclusions:

  • Revascularization for intermittent claudication presents a low but definite risk of procedure-related major amputation.
  • This risk is primarily observed within the first year following the revascularization procedure.
Abstract

Keywords:
AmputationIntermittent claudicationPeripheral arterial diseaseSurgery

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