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Updated: Jan 1, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
[Optimal Imaging Method for Late Gadolinium-enhanced Cardiovascular Magnetic Resonance in Arrhythmic Cases]
1Department of Radiologic Technology, Jichi Medical University Hospital.
Insights
Phase-sensitive inversion recovery (PSIR) imaging effectively reduces arrhythmia-related ghosting artifacts in cardiovascular magnetic resonance (CMR) LGE imaging. This technique improves visualization of mild fibrosis in patients with arrhythmias.
Area of Science:
- Cardiovascular Magnetic Resonance Imaging
- Medical Imaging Artifact Reduction
- Cardiac Electrophysiology
Background:
- Arrhythmia can cause ghosting artifacts in late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging.
- These artifacts complicate the assessment of myocardial fibrosis, particularly in patients with irregular heart rhythms.
Purpose of the Study:
- To determine a procedure for reducing arrhythmia-related ghosting artifacts in LGE CMR.
- To compare the efficacy of different imaging sequences in the presence of arrhythmias.
Main Methods:
- Phantoms were used to examine the causes of ghosting artifacts.
- Inversion recovery gradient echo and phase-sensitive inversion recovery (PSIR) sequences were compared under normal sinus rhythm and premature ventricular contraction (PVC) conditions.
Main Results:
- Premature ventricular contractions (PVCs) induced ghosting artifacts due to irregular trigger intervals.
- A phase-corrected real image in PSIR demonstrated accurate positive contrast for mild fibrosis with minimal ghosting.
- The 2R-R method also reduced ghost artifacts and ensured contrast consistency.
Conclusions:
- PSIR imaging offers an advantage for LGE CMR in patients experiencing arrhythmias.
- PSIR minimizes ghosting artifacts, improving the diagnostic accuracy for myocardial fibrosis.
- The 2R-R method provides an alternative for artifact reduction when PSIR is unavailable.
Abstract:
We determined the procedure to reduce arrhythmia-related ghosting artifacts in the late gadolinium enhancement (LGE) imaging of cardiovascular magnetic resonance (CMR) in patients with arrhythmia by examining the causing factors using phantoms. Inversion recovery gradient echo and phase-sensitive inversion recovery (PSIR) sequences were compared under normal sinus rhythm and premature ventricular contraction (PVC) conditions. Under the PVC condition, trigger interval irregularly performed induced ghosting artifacts. A phase-corrected real image in PSIR, however; demonstrated an accurately positive contrast of pale LGE area indicative of mild fibrosis with minimal ghosting artifacts. The study results indicate that PSIR has an advantage for LGE CMR in patients with arrhythmia. Even without having PSIR method, the 2R-R method ensures consistency of contrast and enables reduction of ghost artifacts.
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