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Related Experiment Videos

A tissue heat transfer model for relating dynamic skin temperature changes to physiological parameters.

S B Wilson1, V A Spence

  • 1Vascular Laboratory, Ninewells Hospital Medical School, Dundee, UK.

Physics in Medicine and Biology
|August 1, 1988
PubMed
Summary

This study presents a new physical and mathematical model for superficial body tissues, linking skin temperature changes to physiological parameters. The model accurately predicts skin temperature and offers a better method for assessing dermal perfusion using transient measurements.

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Area of Science:

  • Biophysics
  • Physiology
  • Mathematical Modeling

Background:

  • Understanding superficial tissue physiology is crucial for various medical applications.
  • Existing models may not fully capture the dynamic interplay of heat transfer, blood perfusion, and metabolism.
  • Accurate measurement of dermal perfusion is essential for diagnosing and monitoring conditions affecting blood flow.

Purpose of the Study:

  • To develop and validate a physical and mathematical model of superficial body tissues.
  • To relate transient skin surface temperature changes to underlying physiological parameters.
  • To assess the utility of transient temperature measurements for evaluating dermal perfusion.

Main Methods:

  • Developed a one-dimensional finite difference model of the bioheat equation for multi-layered superficial tissues (0-10 mm).

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  • Incorporated tissue physiology, structure, and blood supply into the model.
  • Validated model predictions against preliminary thermography data from cold challenge experiments on the volar forearm.

    • Main Results:

    • The model accurately predicts steady-state skin surface temperature, identifying heat transfer from deeper tissues, perfusion, and metabolism as key factors.
    • Model predictions of the skin temperature reheat curve post-cold challenge closely matched experimental thermography data.
    • The model provides a physical basis for the observed shape of the skin temperature reheat curve.

    Conclusions:

    • Transient skin surface temperature measurements offer a more robust indicator of dermal perfusion compared to static measurements.
    • The developed model enhances understanding of heat regulation in superficial tissues.
    • This modeling approach can help reduce the influence of environmental and deep tissue variations on perfusion assessments.