Related Experiment Video
Updated: Jan 1, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Heart failure in primary care: prevalence related to age and comorbidity
Lieke Bosch1, Patricia Assmann1, Wim J C de Grauw1
1Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, The Netherlands.
Background:
Diagnosing heart failure (HF) in primary care can be challenging, especially in elderly patients with comorbidities. Insight in the prevalence, age, comorbidity and routine practice of diagnosing HF in general practice may improve the process of diagnosing HF.
Aim:
To examine the prevalence of HF in relation to ageing and comorbidities, and routine practice of diagnosing HF in general practice.
Methods:
A retrospective cohort study was performed using data from electronic health records of 56 320 adult patients of 11 general practices. HF patients were compared with patients without HF using descriptive analyses and χ2 tests. The following comorbidities were considered: chronic obstructive pulmonary disorder (COPD), diabetes mellitus (DM), hypertension, anaemia and renal function disorder (RFD). Separate analyses were performed for men and women.
Findings:
The point prevalence of HF was 1.2% (95% confidence interval 1.13-1.33) and increased with each age category from 0.04% (18-44 years) to 20.9% (⩾85 years). All studied comorbidities were significantly (P<0.001) more common in HF patients than in patients without HF: COPD (24.1% versus 3.1%), DM (34.7% versus 6.5%), hypertension (52.7% versus 16.0%), anaemia (10.9% versus 2.3%) and RFD (61.8% versus 7.5%). N-terminal pro-BNP (NT-proBNP) was recorded in 38.1% of HF patients.
Conclusions:
HF is highly associated with ageing and comorbidities. Diagnostic use of NT-proBNP in routine primary care seems underutilized. Instruction of GPs to determine NT-proBNP in patients suspected of HF is recommended, especially In elderly patients with comorbidities.
Related Concept Videos
Heart Failure I: Introduction
Pathophysiology of Heart Failure
Heart Failure IV: Classification and Diagnostic Evaluation
Heart Failure III: Clinical Manifestations
Heart Failure II: Pathophysiology
Heart Failure VII: Nursing Interventions
