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Updated: Jan 1, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Two-port intrapericardial left VATS pneumonectomy
Samuele Nicotra1, Giovanni Comacchio2, Giuseppe Natale1
1Thoracic Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Via Giustiniani 2, 35128, Padova, Italy.
This study details an intrapericardial left video-assisted thoracoscopic pneumonectomy for advanced hilar squamous cell carcinoma. The complex procedure, involving intrapericardial vessel control, resulted in an uneventful recovery.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Cardiothoracic Surgery
Background:
- Pneumonectomy is a critical intervention for locally advanced lung cancers invading the pulmonary hilum.
- An intrapericardial approach is sometimes required for safe management of pulmonary vessels when extrapericardial dissection is not feasible.
- Video-assisted thoracoscopic surgery (VATS) offers a minimally invasive option for complex thoracic procedures.
Discussion:
- This case report describes a novel two-incision VATS technique for left pneumonectomy with an intrapericardial approach.
- The technique involved intrapericardial isolation and closure of pulmonary vessels due to proximal involvement.
- Radical lymphadenectomy and bronchial stump coverage with a pericardial flap were integral parts of the procedure.
Key Insights:
- Intrapericardial VATS pneumonectomy is a feasible, albeit complex, approach for managing hilar lung cancers with extensive hilar involvement.
- The described technique facilitates safe handling of critical hilar structures in challenging oncological resections.
- Successful application of this VATS strategy led to a positive patient outcome with early discharge.
Outlook:
- Further research could explore the long-term oncological outcomes and recurrence rates following this specialized VATS technique.
- Standardization of the intrapericardial VATS pneumonectomy approach may expand its applicability in treating advanced lung malignancies.
- This approach may offer a less invasive alternative to open thoracotomy for select patients with complex hilar tumors.
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