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Updated: Jan 1, 2026

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
Published on: April 11, 2018
The impact of body-mass index on the frontal knee alignment estimation using three-dimensional reconstruction based
Thomas Legrand1, Vincent Richard1, Alice Bonnefoy-Mazure2
1Department of Kinesiology, Medicine Faculty, Laval University, Quebec, Quebec, Canada; Center for Interdisciplinary Research in Rehabilitation and Social Integration, Quebec, Quebec, Canada.
Background:
We evaluated the influence of the body-mass index (BMI) on the estimation of the static frontal knee alignment (FKA) using three-dimensional (3D) reconstruction method based on movement analysis.
Methods:
Two-hundred nineteen knees (120 individuals with end-stage osteoarthritis) were analyzed. The validity of the 3D method was evaluated under comparison with a reference method based on weight bearing full-leg length radiography. Extensive statistical analyses (Pearson's correlation, one-way ANOVA, linear regression, boxplot diagram) over four groups of BMI (normal, overweight, obese class I and obese classes II and III) were performed.
Results:
For BMI below 25 kg/m2, the validity of the 3D method was confirmed. For BMI over 25 kg/m2, there was an increasing error of the 3D method, especially for the obese groups affected with a large varus alignment.
Conclusions:
In a biomechanical context of movement analysis, the results of the study suggest that the 3D method may represent a satisfying alternative to the full-leg radiograph method with limitations regarding to BMI over 25 kg/m2.

