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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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Traumatic kidney injuries: A systematic review and meta-analysis
Patrizio Petrone1, Javier Perez-Calvo1, Collin E M Brathwaite1
1Department of Surgery, NYU Langone Health - NYU Winthrop Hospital, NYU Long Island School of Medicine, Mineola, NY, USA.
International Journal of Surgery (London, England)
|December 25, 2019
Summary
This review analyzes traumatic kidney injuries, finding non-operative management effective for reducing mortality and improving patient quality of life. It covers incidence, diagnosis, and treatment of renal trauma.
Area of Science:
- Urology
- Trauma Surgery
- Nephrology
Background:
- Traumatic kidney injury (TKI) presents diverse injury patterns and is infrequent.
- Understanding TKI incidence, mechanisms, diagnostics, and treatments is crucial.
- Analysis of mortality rates in patients with renal trauma is essential.
Purpose of the Study:
- To systematically review the literature on traumatic kidney injuries.
- To conduct a meta-analysis of traumatic kidney injuries.
- To analyze mortality rates associated with renal trauma.
Main Methods:
- Literature search of PubMed, Embase, and Scopus databases (1963-2018).
- Inclusion of original articles on human subjects; exclusion of reviews, case reports, and pediatric/cancer-related injuries.
- MeSH terms: renal trauma, kidney trauma, blunt renal trauma, penetrating renal trauma.
Main Results:
- 46 articles and 48,660 patients were included.
- Blunt trauma (80.5%) was more common than penetrating trauma (19.5%).
- Overall mortality rate for renal trauma was 6.4%.
Conclusions:
- Non-operative management is the standard for renal trauma, improving outcomes.
- This approach reduces unnecessary nephrectomies and enhances quality of life.
- Angioembolization or nephrorrhaphy are key invasive treatments when needed.
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