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Investigating the Potential of Singly Curved Thin Piezoelectric Transducers for Energy Harvesting and Structural Health Monitoring
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Biodegradable nanofiber-based piezoelectric transducer.

Eli J Curry1, Thinh T Le2, Ritopa Das1

  • 1Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269.

Proceedings of the National Academy of Sciences of the United States of America
|December 25, 2019
PubMed
Summary

Biodegradable piezoelectric poly(l-lactic acid) nanofibers offer a safe alternative for implantable medical devices. These advanced nanofibers enable sensitive pressure sensors and drug-delivery ultrasonic transducers, avoiding toxic materials and invasive removal surgeries.

Keywords:
PLLAbiodegradablepiezoelectricpressure sensorsultrasound transducer

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Medical Devices

Background:

  • Piezoelectric materials are crucial for implantable medical devices.
  • Current piezoelectric materials pose safety risks due to toxicity and non-degradability, necessitating surgical removal.
  • This limits their long-term use and can cause tissue damage.

Purpose of the Study:

  • To develop biodegradable and biocompatible piezoelectric nanofibers from poly(l-lactic acid) (PLLA).
  • To achieve controllable, efficient, and stable piezoelectric performance in PLLA nanofibers.
  • To demonstrate novel device applications for these advanced nanomaterials.

Main Methods:

  • Utilized a materials processing strategy for PLLA nanofibers.
  • Employed device assembly and electronic integration techniques.
  • Fabricated and tested biodegradable pressure sensors and ultrasonic transducers.

Main Results:

  • Successfully created piezoelectric PLLA nanofibers with excellent performance.
  • Developed a highly sensitive biodegradable pressure sensor for physiological monitoring.
  • Demonstrated a biodegradable ultrasonic transducer for blood-brain barrier opening to enhance drug delivery.

Conclusions:

  • PLLA nanofibers represent a powerful, safe platform for advanced medical applications.
  • These biodegradable piezoelectric materials overcome limitations of conventional materials.
  • Significant potential impact on drug delivery, tissue engineering, and implantable devices.