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Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for

Seung Yong Shin1,2, Kyeong Seon Ga1, In Young Kim1

  • 1Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Scientific Reports
|December 25, 2019
PubMed

Insights

Cirrhosis, poor diet adherence, brown rectal effluent, and longer time since last bowel movement predict inadequate bowel preparation with low-volume polyethylene glycol (PEG) plus ascorbic acid. These factors can guide interventions to improve colonoscopy prep quality.

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Clinical Research

Background:

  • Low-volume polyethylene glycol (PEG) plus ascorbic acid solutions are standard for colonoscopy preparation.
  • Predicting inadequate bowel preparation is crucial for effective colonoscopy.

Purpose of the Study:

  • To identify pre-endoscopic factors predicting inadequate bowel preparation in patients receiving low-volume PEG plus ascorbic acid.

Main Methods:

  • Prospective study conducted at Gangnam Severance Hospital, Korea.
  • 715 patients undergoing outpatient colonoscopy received low-volume PEG plus ascorbic acid.
  • Bowel preparation timing (split-dose vs. same-day) varied based on colonoscopy schedule.

Main Results:

  • 19.3% of patients had inadequate bowel preparation.
  • Independent predictors included cirrhosis (OR 4.943), low compliance (<70%) with a low-residual diet (OR 2.165), brown rectal effluent (OR 7.604), and a longer time interval (≥2 hours) since last defecation (OR 1.841).

Conclusions:

  • Cirrhosis, poor dietary compliance, brown effluent, and prolonged time since last bowel movement are significant predictors of inadequate bowel preparation.
  • These findings can inform targeted interventions to enhance bowel cleansing quality before colonoscopy.

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