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Ureteropyeloscopic tumour treatment
H Mathiasen1, P C Frimodt-Möller, H V Nielsen
1Department of Surgery, Kolding Hospital, Denmark.
Scandinavian Journal of Urology and Nephrology. Supplementum
|January 1, 1988
Summary
Topical chemotherapy using Epodyl via ureteropyeloscopy effectively treated upper urinary tract transitional cell tumors in two patients. Ureteric tumors showed complete response, while a pelvic papilloma partially responded.
Area of Science:
- Urology
- Oncology
- Chemotherapy
Background:
- Transitional cell tumors of the upper urinary tract present a clinical challenge.
- Topical chemotherapy is an alternative treatment modality for localized urothelial neoplasms.
Observation:
- Ureteropyeloscopy allowed for direct visualization and treatment delivery.
- Epodyl was instilled into the renal pelvis and ureter using a ureteric catheter.
Findings:
- Complete resolution of ureteric transitional cell tumors was observed.
- A pelvic papilloma demonstrated a significant reduction in size, measuring approximately 1 mm post-treatment.
Implications:
- Ureteropyeloscopy with topical chemotherapy is a potentially effective and safe treatment for upper urinary tract tumors.
- This approach may offer a minimally invasive option for managing localized urothelial cancers.