Related Experiment Video
Updated: Jan 1, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
[Application of cardiac assist device and its biomechanics research for heart failure]
Ying Chen1, Zhongjie Yin2, Wenchang Tan1
1Shenzhen Graduate School, Peking University, Shenzhen, Guangdong 518055, P.R.China;College of Engineering, Peking University, Beijing 100871, P.R.China.
Insights
Cardiac assist devices are crucial for treating heart failure (HF). This review covers their current use, challenges, and future directions, offering insights for device improvement and clinical application.
Area of Science:
- Cardiovascular Medicine
- Biomedical Engineering
- Medical Devices
Background:
- Heart failure (HF) is a significant clinical challenge requiring advanced treatment options.
- Cardiac assist devices (CADs) represent a vital therapeutic modality for managing advanced HF.
- The clinical application of CADs has expanded, necessitating a comprehensive review of their status.
Purpose of the Study:
- To review the current application status, challenges, and future trends of cardiac assist devices.
- To provide an overview of CAD classification, research achievements, and clinical indications.
- To summarize recent advancements in heart biomechanics and hemodynamic studies related to CADs.
Main Methods:
- Literature review of cardiac assist device applications and research.
- Analysis of existing problems and future development trends in CAD technology.
- Synthesis of biomechanical heart indexes and new HF treatment approaches.
- Review of recent hemodynamic studies concerning cardiac assist devices.
Main Results:
- Cardiac assist devices are established treatments for heart failure with evolving clinical indications.
- Current challenges include device limitations, surgical complexity, and long-term outcomes.
- Future trends focus on device miniaturization, improved biocompatibility, and advanced control systems.
- Hemodynamic studies are crucial for understanding device-patient interactions and optimizing performance.
Conclusions:
- Cardiac assist devices offer significant benefits for heart failure patients.
- Addressing current limitations and embracing technological advancements will enhance CAD efficacy.
- Further research into biomechanics and hemodynamics is essential for optimizing device design and clinical integration.
- This review provides valuable references for improving cardiac assist device structure and clinical use.
Abstract:
As an important means of treating heart failure (HF), cardiac assist device has been widely used in clinic. This paper reviews the application status, existing problems and future development trend of cardiac assist devices, including the classification of cardiac assist devices, representative research achievements and indications of the assist devices. It also summarizes the biomechanical indexes of the heart and the new approaches and methods for treating heart failure, as well as the hemodynamic studies of cardiac assist devices in recent years. The research findings provide references for further optimization of cardiac assist device structure and clinical application of the device.
Related Concept Videos
Cardiomyopathy II: Dilated Cardiomyopathy
Pathophysiology of Heart Failure
Cardiomyopathy V: Interprofessional Care
Heart Failure VI: Adjunct Therapies
Heart Failure V: Medical Management
Heart Failure II: Pathophysiology

