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Dectin-1 Binding to Annexins on Apoptotic Cells Induces Peripheral Immune Tolerance via NADPH Oxidase-2

Kevin Bode1, Fatmire Bujupi1, Corinna Link1

  • 1Division of Immunogenetics, Research Program Immunology and Cancer, German Cancer Research Center, 69120 Heidelberg, Germany; Faculty of Biosciences, Ruprecht Karls University Heidelberg, 69120 Heidelberg, Germany.

Cell Reports
|December 26, 2019
PubMed

Keywords:
Dectin-1NOX-2SYKannexin (A1, A5, and A13)apoptotic cellsautoimmunitybiased agonismdendritic cellsperipheral immune tolerancereactive oxygen species

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