Related Experiment Video
Updated: Aug 12, 2026

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
Published on: February 19, 2017
[Spatial distribution of hemoglobin in children aged 0-2 years in China in 2013]
Shujuan Li1, Dongmei Yu1, Liyun Zhao1
1National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Insights
Hemoglobin levels in Chinese children aged 0-2 vary significantly by region, with distinct high and low value areas identified. This spatial distribution, crucial for anemia assessment, shows no correlation with altitude.
Area of Science:
- Pediatric Nutrition
- Hematology
- Geographic Epidemiology
Background:
- Anemia diagnosis in children requires region-specific hemoglobin reference values.
- Understanding spatial variations in hemoglobin is essential for targeted public health interventions.
Purpose of the Study:
- To map the spatial distribution of hemoglobin levels in children aged 0-2 years across China.
- To identify regional differences in hemoglobin values to aid in anemia assessment.
Main Methods:
- Analysis of hemoglobin data from 13,951 children (aged 0-2) from the 2010-2013 National Nutrition and Health Survey.
- Utilized SAS for statistical analysis and Geographic Information System (GIS) with inverse distance weighted (IDW) spatial interpolation to create distribution maps.
Main Results:
- Average hemoglobin values ranged from 112.02 to 139.03 g/L.
- Highest values observed in Heilongjiang and Gansu provinces; distinct high-value areas identified in inland and coastal regions.
- Low-value hemoglobin areas were mapped in central and southern China, as well as parts of the northeast and north.
Conclusions:
- Significant regional disparities in children's hemoglobin levels exist across China.
- Spatial mapping reveals localized high and low hemoglobin value zones.
- No significant correlation found between hemoglobin distribution and altitude.
Objective:
To obtain hemoglobin values in different regions of China is of great guiding value for judging anemia in children in different regions.
Methods:
A total of 13 951 children aged 0-2 years old(female 6759, male 7192, urban area 6866, rural area 7085) in the 2010-2013 National Nutrition and Health Survey was analyzed the characteristics of hemoglobin spatial differentiation. SAS was used to analyze the data of children's hemoglobin result. Geographic Information System(GIS)spatial analysis method was used to form the spatial distribution map of hemoglobin mean values at 55 monitoring points, and inverse distance weighted spatial interpolation(IDW)method was used to obtain the spatial distribution map of children's hemoglobin in China.
Results:
Based on the data of 13 951 children aged 0-2 years in the National Nutrition and Health Survey, it was found that the average hemoglobin value of Chinese children ranged from 112. 02 to 139. 03 g/L. The average hemoglobin value of Yi 'an County in Heilongjiang Province(139. 04 ± 1. 22 g/L) and Kangle County in Gansu Province(132. 43 ± 0. 82 g/L) was the highest, followed by Shanxi, Yunnan, Anhui, Qinghai and Fujian Provinces(124. 03-128. 72 g/L). The result of spatial interpolation of hemoglobin for children aged 0-2 in China showed that the hemoglobin of children aged0-2 in China showed spatial differences, forming inland high value areas with Heilongjiang, Gansu-Qinghai, Shanxi and Yunnan as the core, Anhui-Jiangsu-ZhejiangFujian coastal high value areas. Low-value areas of hemoglobin were formed in eastern Sichuan-Chongqing-western Hubei-southern Shaanxi, Inner Mongolia-Shanxi-Shaanxi, Beijing-Hebei, Jilin-Liaoning, southern Guangdong and Hainan. There was no significant correlation between the spatial distribution of hemoglobin and altitude in children aged 0-2 years in China in 2013.
Conclusion:
The spatial distribution of hemoglobin in children aged 0-2 years in China has significant spatial difference characteristics between different regions, with local higher value region and lower value region distribution, which has no significant correlation with altitude.
Related Concept Videos
Erythropoiesis
Overview of Hematopoiesis
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...
Hemoglobin
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
Factors Affecting Erythropoiesis
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
Oxygen Transport in the Blood
Pharmacokinetics in Pediatric Patients: Drug Distribution

