Cerebral blastomycosis. A report of 2 cases

Following recent documentation of blastomycosis in the RSA, a report of a further 2 cases in Natal is presented. The unusual feature of both cases was the presence of central nervous system involvement. In the first patient intracerebral involvement occurred after apparent good response to ketoconazole when he defaulted from therapy after 3 months. The second patient presented with cerebral involvement and died soon after admission to hospital.