Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

1.2K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
1.2K
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

948
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
948

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Who receives psychiatry-focused pharmacogenomic testing, and is it associated with prescribing patterns and acute care utilisation in depression? Real-world evidence from a large health system.

EBioMedicine·2026
Same author

Population Estimates and Hypertension and Diabetes Prevalence: Cross-Sectional Quantitative Study Comparing Electronic Health Record-Derived Counts, Census, and Centers for Disease Control and Prevention Population Level Analysis and Community Estimates.

JMIR public health and surveillance·2026
Same author

Topology-optimized distributed 3d anisotropic Raman emission.

Optics express·2026
Same author

Inverse design of multiresonance filters via quasi-normal mode theory.

Optics express·2026
Same author

Eigenvalue-accelerated LDOS optimization of high-<i>Q</i> optical resonances.

Optics express·2026
Same author

Among individuals who die of COVID-19, is the percentage who had diabetes actually higher than in those dying of other viral infections?

Research square·2026

Related Experiment Video

Updated: Jan 1, 2026

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
06:15

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

Published on: June 16, 2023

2.4K

Limits to surface-enhanced Raman scattering near arbitrary-shape scatterers.

Jérôme Michon, Mohammed Benzaouia, Wenjie Yao

    Optics Express
    |December 28, 2019
    PubMed
    Summary

    Surface-enhanced Raman scattering (SERS) boosts low Raman spectroscopy efficiency using nanostructures. This study defines upper bounds for SERS enhancement, identifying optimal materials like silver and aluminum for different wavelengths.

    More Related Videos

    Observation and Analysis of Blinking Surface-enhanced Raman Scattering
    05:52

    Observation and Analysis of Blinking Surface-enhanced Raman Scattering

    Published on: January 11, 2018

    7.7K
    Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
    11:44

    Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

    Published on: March 20, 2015

    21.0K

    Related Experiment Videos

    Last Updated: Jan 1, 2026

    Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
    06:15

    Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

    Published on: June 16, 2023

    2.4K
    Observation and Analysis of Blinking Surface-enhanced Raman Scattering
    05:52

    Observation and Analysis of Blinking Surface-enhanced Raman Scattering

    Published on: January 11, 2018

    7.7K
    Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
    11:44

    Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

    Published on: March 20, 2015

    21.0K

    Area of Science:

    • Plasmonics and Nanophotonics
    • Spectroscopy and Sensing

    Background:

    • Raman spectroscopy suffers from low efficiency, limiting its practical applications.
    • Surface-enhanced Raman scattering (SERS) utilizes plasmonic nanostructures to amplify Raman signals.
    • The enhancement factor in SERS is highly dependent on the geometry and material of the nanoscatterer.

    Purpose of the Study:

    • To establish fundamental upper bounds for Raman enhancement achievable with arbitrary-shaped scatterers.
    • To identify optimal materials and geometries for maximizing SERS efficiency across different wavelength regions.
    • To explore design opportunities for future SERS nanostructure development.

    Main Methods:

    • Theoretical derivation of analytical upper bounds for Raman enhancement based on scatterer material properties and molecule-scatterer distance.
    • Investigation of enhancement bounds for both single, arbitrary-shaped scatterers and periodic arrangements.
    • Numerical computations to compare theoretical bounds with performance of simple geometries.

    Main Results:

    • Fundamental upper bounds on Raman enhancement were determined, dependent solely on material constants and separation distance.
    • Silver was identified as optimal for visible wavelengths, while aluminum is superior in the near-UV region.
    • The analytical bound scales with scatterer volume and the inverse sixth power of the molecule-scatterer distance.

    Conclusions:

    • Current simple SERS geometries do not reach the theoretical enhancement limits, indicating room for improved nanostructure design.
    • For periodic scatterers, distinct bounds were derived, with the tighter bound dictating the maximum achievable enhancement.
    • An optimal period for periodic scatterers was suggested, dependent on the scatterer's volume.