Related Experiment Video
Updated: Jan 1, 2026
Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention
Published on: September 11, 2017
Parietal conditioning enhances motor surround inhibition
Nivethida Thirugnanasambandam1, Giorgio Leodori2, Traian Popa1
1Human Motor Control Section, National Institute of Neurological Disorders and Stroke (NINDS), NIH, Bethesda, MD, USA.
Background:
Motor surround inhibition (mSI) is a phenomenon supportive for executing selective finger movements, wherein synergist muscles are selectively facilitated while surround muscles are inhibited. Previous studies of conditioning inputs to several intracortical and cortico-cortical inhibitory networks did not show an influence on mSI. The inhibitory posterior parietal-motor network, which is crucial for executing fine movements, however, has not been studied.
Objective/Hypothesis:
To investigate the role of inhibitory posterior parietal-motor network in mSI. We hypothesized that conditioning this inhibitory network would enhance mSI.
Methods:
11 healthy adults completed study. mSI was elicited by applying a TMS pulse over the motor cortex coupled with or without a conditioning input to an inhibitory spot in the posterior parietal cortex at 2 or 4 ms interval.
Results:
Conditioning input to the posterior parietal cortex increased mSI by ∼20% CONCLUSION: The inhibitory posterior parietal-motor network appears to contribute to the genesis of mSI.
More Related Videos
09:43Reversible Cooling-induced Deactivations to Study Cortical Contributions to Obstacle Memory in the Walking Cat
Published on: December 11, 2017
08:55Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
Published on: February 8, 2018
Related Concept Videos
01:14Motor and Sensory Areas of the Cortex
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
01:24Somatosensory, Motor, and Association Cortex
01:28Major Somatic Sensory Pathways
01:21Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...